منابع مشابه
Preventive effect of omega-3 fatty acids on ethinyl estradiolinduced hepatosteatosis in female wistar rat
BACKGROUND: Hepatic steatosis due to estrogen therapyincreases the activity of inflammatory markers, particularly theactivity of TNFα which in turn induces more lipogenesis.Omega-3 fatty acids are among the negative regulators of hepaticlipogenesis. OBJECTIVES: In this research, the preventive effectof omega-3 fatty acids on estrogen-induced steatosis in rats wasevaluated. METHODS:2 mg/kg. BW/S...
متن کاملMicrovascular retinopathy in the Zucker diabetic fatty rat.
PURPOSE To determine if quantifiable morphometric signs of retinopathy occur in the Zucker diabetic fatty rat (ZDF/Gmi-fa, formerly designated ZDF/Drt), a partially inbred strain in which the genetic propensity for diabetes is only expressed in obese males. METHODS Retired diabetic (ZDF/Gmi-fa) and control lean Zucker (fa/+) breeder rats were examined for quantifiable evidence of microvascula...
متن کاملRespiratory muscle weakness in the Zucker diabetic fatty rat.
The obesity epidemic is considered one of the most serious public health problems of the modern world. Physical therapy is the most accessible form of treatment; however, compliance is a major obstacle due to exercise intolerance and dyspnea. Respiratory muscle atrophy is a cause of dyspnea, yet little is known of obesity-induced respiratory muscle dysfunction. Our objective was to investigate ...
متن کاملThe Effect of Dietary Polyunsaturated Fatty Acid on Skin Wound Healing in Chronic Diabetic Rat
The potential role of omega – 3 (ω-3) and omega - 6(ω-6) fatty acids on wound healing is of interest and controversial. In the present study, the effect of dietary intake of fish oil (ω-3 diet ) and corn oil (ω-6 diet) on skin wound healing has been investigated in rat. This experimental study was performed on four groups of male rats (one normal group and three diabetic groups). Diabetes was i...
متن کاملsubstrains of Wistar-Kyoto rat
Background. Goodpasture's, or antiglomerular basement membrane (GBM), disease presents with rapidly progressive glomerulonephritis, and is caused by autoimmunity to the NCI domain of the 0:3 chain of type IV collagen. In order to investigate mechanisms involved in the induction and regulation of glomerulonephritis, experimental models of Goodpasture's disease have been developed in the rat whic...
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ژورنال
عنوان ژورنال: ILAR Journal
سال: 1990
ISSN: 1084-2020
DOI: 10.1093/ilar.32.3.9